Silence Therapeutics plc, a biotechnology company, focuses on the discovery and development of novel ribonucleic acid (RNA) therapeutics in hematology, cardiovascular, and other rare and metabolic indications. The company's platform includes mRNAi GalNAc Oligonucleotide Discovery platform designed to accurately target specific disease-associated genes in the liver. It designs short interfering RNA molecules to harness the body's natural mechanism of RNA interference, and degrading messenger RNA molecules that encode specific targeted disease-associated proteins in a cell. The company is developing various product candidates, including SLN360, which is Phase I clinical trials for the treatment of cardiovascular disease with high lipoprotein; SLN124 that is in Phase I clinical trials for the treatment of non-transfusion dependent thalassemia, and Phase I clinical trials for the treatment of myelodysplastic syndrome; and SLN124 for the treatment of polycythemia vera. It has collaboration agreements with AstraZeneca PLC to discover, develop, and commercialize small interfering RNA therapeutics for the treatment of cardiovascular, renal, metabolic, and respiratory diseases; and Mallinckrodt Pharma IP Trading DAC to develop and commercialize RNAi drug targets designed to silence the complement cascade in complement-mediated disorders. The company also has a collaboration with Hansoh Pharmaceutical Group Company Limited to develop siRNAs for three undisclosed targets leveraging Silence's mRNAi GOLD platform. The company was formerly known as SR Pharma plc and changed its name to Silence Therapeutics plc in May 2007. Silence Therapeutics plc is headquartered in London, the United Kingdom.
As of Nov 2024 Silence Therapeutics plc has a market cap of $456.55 M. This makes Silence Therapeutics plc the world's most valuable company by market cap according to our data. The market capitalization, commonly called market cap, is the total market value of a publicly traded company's outstanding shares and is commonly used to measure how much a company is worth.
Date | Market cap |
---|---|
20 Nov 2024 | $323.88 M |
19 Nov 2024 | $325.75 M |
18 Nov 2024 | $515.03 M |
15 Nov 2024 | $593.55 M |
14 Nov 2024 | $653.37 M |
13 Nov 2024 | $712.26 M |
12 Nov 2024 | $757.6 M |
11 Nov 2024 | $819.75 M |
08 Nov 2024 | $818.82 M |
07 Nov 2024 | $832.84 M |
06 Nov 2024 | $840.79 M |
05 Nov 2024 | $823.49 M |
04 Nov 2024 | $833.31 M |
01 Nov 2024 | $826.3 M |
31 Oct 2024 | $808.54 M |
30 Oct 2024 | $810.41 M |
29 Oct 2024 | $841.25 M |
28 Oct 2024 | $844.53 M |
25 Oct 2024 | $844.99 M |
24 Oct 2024 | $839.85 M |
23 Oct 2024 | $842.19 M |
22 Oct 2024 | $841.25 M |
21 Oct 2024 | $839.85 M |
18 Oct 2024 | $840.79 M |
17 Oct 2024 | $864.62 M |
16 Oct 2024 | $865.56 M |
15 Oct 2024 | $854.81 M |
14 Oct 2024 | $877.71 M |
11 Oct 2024 | $918.37 M |
10 Oct 2024 | $897.34 M |
09 Oct 2024 | $902.01 M |
08 Oct 2024 | $909.02 M |
07 Oct 2024 | $869.76 M |
04 Oct 2024 | $871.16 M |
03 Oct 2024 | $900.61 M |
02 Oct 2024 | $859.95 M |
01 Oct 2024 | $852 M |
30 Sep 2024 | $849.67 M |
27 Sep 2024 | $852.94 M |
26 Sep 2024 | $814.61 M |
25 Sep 2024 | $844.53 M |
24 Sep 2024 | $852.47 M |
23 Sep 2024 | $841.25 M |
20 Sep 2024 | $853.87 M |
19 Sep 2024 | $855.74 M |
18 Sep 2024 | $853.41 M |
17 Sep 2024 | $852 M |
16 Sep 2024 | $852 M |
13 Sep 2024 | $873.5 M |
12 Sep 2024 | $868.36 M |
11 Sep 2024 | $867.43 M |
10 Sep 2024 | $878.64 M |
09 Sep 2024 | $885.19 M |
06 Sep 2024 | $871.63 M |
05 Sep 2024 | $880.98 M |
04 Sep 2024 | $899.67 M |
03 Sep 2024 | $895.94 M |
30 Aug 2024 | $839.2 M |
29 Aug 2024 | $824.26 M |
28 Aug 2024 | $828.21 M |
27 Aug 2024 | $835.25 M |
26 Aug 2024 | $804.04 M |
23 Aug 2024 | $712.16 M |
22 Aug 2024 | $682.7 M |
21 Aug 2024 | $696.33 M |
20 Aug 2024 | $698.97 M |
19 Aug 2024 | $698.97 M |
16 Aug 2024 | $689.74 M |
15 Aug 2024 | $737.22 M |
14 Aug 2024 | $714.8 M |
13 Aug 2024 | $729.74 M |
12 Aug 2024 | $724.47 M |
09 Aug 2024 | $726.23 M |
08 Aug 2024 | $734.14 M |
07 Aug 2024 | $739.41 M |
06 Aug 2024 | $785.57 M |
05 Aug 2024 | $755.24 M |
02 Aug 2024 | $828.65 M |
01 Aug 2024 | $869.98 M |
31 Jul 2024 | $901.19 M |
30 Jul 2024 | $874.81 M |
29 Jul 2024 | $905.58 M |
26 Jul 2024 | $922.73 M |
25 Jul 2024 | $924.05 M |
24 Jul 2024 | $927.12 M |
23 Jul 2024 | $955.7 M |
22 Jul 2024 | $941.63 M |
19 Jul 2024 | $908.66 M |
18 Jul 2024 | $892.84 M |
17 Jul 2024 | $897.67 M |
16 Jul 2024 | $913.94 M |
15 Jul 2024 | $900.75 M |
12 Jul 2024 | $905.58 M |
11 Jul 2024 | $930.64 M |
10 Jul 2024 | $879.65 M |
09 Jul 2024 | $845.8 M |
08 Jul 2024 | $833.49 M |
05 Jul 2024 | $800.52 M |
03 Jul 2024 | $789.97 M |
02 Jul 2024 | $793.92 M |
01 Jul 2024 | $823.82 M |
28 Jun 2024 | $835.25 M |
27 Jun 2024 | $835.25 M |
26 Jun 2024 | $804.91 M |
25 Jun 2024 | $877.01 M |
24 Jun 2024 | $895.03 M |
21 Jun 2024 | $863.82 M |
20 Jun 2024 | $830.85 M |
18 Jun 2024 | $830.85 M |
17 Jun 2024 | $835.25 M |
14 Jun 2024 | $848.44 M |
13 Jun 2024 | $866.9 M |
12 Jun 2024 | $914.38 M |
11 Jun 2024 | $916.57 M |
10 Jun 2024 | $913.94 M |
07 Jun 2024 | $900.31 M |
06 Jun 2024 | $892.4 M |
05 Jun 2024 | $879.21 M |
04 Jun 2024 | $872.17 M |
03 Jun 2024 | $906.9 M |
31 May 2024 | $922.73 M |
30 May 2024 | $958.78 M |
29 May 2024 | $946.91 M |
28 May 2024 | $971.08 M |
24 May 2024 | $963.17 M |
23 May 2024 | $967.13 M |
22 May 2024 | $1.02 B |
21 May 2024 | $1.05 B |
20 May 2024 | $1.03 B |
17 May 2024 | $1.01 B |
16 May 2024 | $892.84 M |
15 May 2024 | $869.1 M |
14 May 2024 | $822.79 M |
13 May 2024 | $810.33 M |
10 May 2024 | $825.51 M |
09 May 2024 | $893.23 M |
08 May 2024 | $879.61 M |
07 May 2024 | $863.65 M |
06 May 2024 | $852.37 M |
03 May 2024 | $855.87 M |
02 May 2024 | $829.01 M |
01 May 2024 | $833.68 M |
30 Apr 2024 | $850.81 M |
29 Apr 2024 | $851.59 M |
26 Apr 2024 | $841.08 M |
25 Apr 2024 | $841.47 M |
24 Apr 2024 | $866.77 M |
23 Apr 2024 | $876.11 M |
22 Apr 2024 | $875.72 M |
19 Apr 2024 | $881.17 M |
18 Apr 2024 | $857.04 M |
17 Apr 2024 | $839.13 M |
16 Apr 2024 | $827.07 M |
15 Apr 2024 | $804.1 M |
12 Apr 2024 | $862.88 M |
11 Apr 2024 | $870.27 M |
10 Apr 2024 | $823.18 M |
09 Apr 2024 | $817.34 M |
08 Apr 2024 | $833.3 M |
05 Apr 2024 | $823.18 M |
04 Apr 2024 | $833.68 M |
03 Apr 2024 | $829.79 M |
02 Apr 2024 | $826.68 M |
01 Apr 2024 | $844.58 M |
28 Mar 2024 | $840.69 M |
27 Mar 2024 | $849.25 M |
26 Mar 2024 | $840.3 M |
25 Mar 2024 | $850.81 M |
22 Mar 2024 | $853.53 M |
21 Mar 2024 | $883.11 M |
20 Mar 2024 | $891.68 M |
19 Mar 2024 | $908.41 M |
18 Mar 2024 | $934.49 M |
15 Mar 2024 | $888.95 M |
14 Mar 2024 | $927.48 M |
13 Mar 2024 | $996.76 M |
12 Mar 2024 | $1.01 B |
11 Mar 2024 | $943.83 M |
08 Mar 2024 | $995.98 M |
07 Mar 2024 | $983.14 M |
06 Mar 2024 | $972.24 M |
05 Mar 2024 | $1.01 B |
04 Mar 2024 | $1.02 B |
01 Mar 2024 | $1 B |
29 Feb 2024 | $991.31 M |
28 Feb 2024 | $999.88 M |
27 Feb 2024 | $994.04 M |
26 Feb 2024 | $934.49 M |
23 Feb 2024 | $913.08 M |
22 Feb 2024 | $897.9 M |
21 Feb 2024 | $926.32 M |
20 Feb 2024 | $952 M |
16 Feb 2024 | $862.88 M |
15 Feb 2024 | $851.98 M |
14 Feb 2024 | $854.31 M |
13 Feb 2024 | $875.72 M |
12 Feb 2024 | $887.4 M |
09 Feb 2024 | $857.82 M |
08 Feb 2024 | $825.12 M |
07 Feb 2024 | $818.89 M |
06 Feb 2024 | $823.18 M |
05 Feb 2024 | $833.68 M |
02 Feb 2024 | $867.16 M |
01 Feb 2024 | $839.52 M |
31 Jan 2024 | $876.11 M |
30 Jan 2024 | $758.96 M |
29 Jan 2024 | $735.6 M |
26 Jan 2024 | $743 M |
25 Jan 2024 | $739.5 M |
24 Jan 2024 | $744.17 M |
23 Jan 2024 | $731.71 M |
22 Jan 2024 | $735.21 M |
19 Jan 2024 | $716.53 M |
18 Jan 2024 | $740.66 M |
17 Jan 2024 | $703.69 M |
16 Jan 2024 | $694.74 M |
12 Jan 2024 | $688.9 M |
11 Jan 2024 | $676.83 M |
10 Jan 2024 | $710.31 M |
09 Jan 2024 | $684.62 M |
08 Jan 2024 | $700.58 M |
05 Jan 2024 | $697.46 M |
04 Jan 2024 | $689.29 M |
03 Jan 2024 | $707.97 M |
02 Jan 2024 | $721.98 M |
29 Dec 2023 | $676.06 M |
28 Dec 2023 | $662.43 M |
27 Dec 2023 | $687.73 M |
26 Dec 2023 | $661.27 M |
22 Dec 2023 | $634.02 M |
21 Dec 2023 | $648.03 M |
20 Dec 2023 | $633.63 M |
19 Dec 2023 | $651.92 M |
18 Dec 2023 | $660.1 M |
15 Dec 2023 | $623.9 M |
14 Dec 2023 | $611.84 M |
13 Dec 2023 | $583.81 M |
12 Dec 2023 | $600.55 M |
11 Dec 2023 | $574.08 M |
08 Dec 2023 | $564.35 M |
07 Dec 2023 | $567.47 M |
06 Dec 2023 | $555.4 M |
05 Dec 2023 | $546.84 M |
04 Dec 2023 | $536.33 M |
01 Dec 2023 | $527.38 M |
30 Nov 2023 | $500.91 M |
29 Nov 2023 | $500.52 M |
28 Nov 2023 | $493.52 M |
27 Nov 2023 | $469.77 M |
24 Nov 2023 | $457.51 M |
22 Nov 2023 | $449.54 M |
21 Nov 2023 | $418.79 M |
20 Nov 2023 | $385.71 M |
17 Nov 2023 | $354.18 M |
16 Nov 2023 | $361.96 M |
15 Nov 2023 | $366.63 M |
14 Nov 2023 | $358.85 M |
13 Nov 2023 | $350.68 M |
10 Nov 2023 | $358.07 M |
09 Nov 2023 | $389.21 M |
08 Nov 2023 | $398.55 M |
07 Nov 2023 | $381.42 M |
06 Nov 2023 | $392.71 M |
03 Nov 2023 | $358.07 M |
02 Nov 2023 | $358.07 M |
01 Nov 2023 | $337.05 M |
31 Oct 2023 | $260.77 M |
30 Oct 2023 | $272.45 M |
27 Oct 2023 | $277.12 M |
26 Oct 2023 | $273.61 M |
25 Oct 2023 | $282.57 M |
24 Oct 2023 | $270.11 M |
23 Oct 2023 | $263.1 M |
20 Oct 2023 | $277.51 M |
19 Oct 2023 | $287.24 M |
18 Oct 2023 | $303.97 M |
17 Oct 2023 | $323.04 M |
16 Oct 2023 | $312.92 M |
13 Oct 2023 | $302.03 M |
12 Oct 2023 | $322.65 M |
11 Oct 2023 | $334.72 M |
10 Oct 2023 | $367.41 M |
09 Oct 2023 | $363.52 M |
06 Oct 2023 | $365.86 M |
05 Oct 2023 | $359.63 M |
04 Oct 2023 | $354.57 M |
03 Oct 2023 | $352.62 M |
02 Oct 2023 | $358.07 M |
29 Sep 2023 | $366.34 M |
28 Sep 2023 | $364.1 M |
27 Sep 2023 | $361.86 M |
26 Sep 2023 | $371.93 M |
25 Sep 2023 | $369.7 M |
22 Sep 2023 | $400.66 M |
21 Sep 2023 | $387.98 M |
20 Sep 2023 | $399.17 M |
19 Sep 2023 | $395.06 M |
18 Sep 2023 | $362.98 M |
15 Sep 2023 | $371.19 M |
14 Sep 2023 | $372.31 M |
13 Sep 2023 | $368.2 M |
12 Sep 2023 | $348.81 M |
11 Sep 2023 | $334.26 M |
08 Sep 2023 | $315.23 M |
07 Sep 2023 | $317.1 M |
06 Sep 2023 | $302.17 M |
05 Sep 2023 | $320.45 M |
01 Sep 2023 | $317.1 M |
31 Aug 2023 | $332.02 M |
30 Aug 2023 | $334.63 M |
29 Aug 2023 | $342.84 M |
28 Aug 2023 | $315.98 M |
25 Aug 2023 | $343.58 M |
24 Aug 2023 | $321.2 M |
23 Aug 2023 | $316.72 M |
22 Aug 2023 | $278.67 M |
21 Aug 2023 | $260.76 M |
18 Aug 2023 | $260.76 M |
17 Aug 2023 | $254.05 M |
16 Aug 2023 | $242.49 M |
15 Aug 2023 | $228.31 M |
14 Aug 2023 | $227.94 M |
11 Aug 2023 | $222.34 M |
10 Aug 2023 | $223.83 M |
09 Aug 2023 | $207.79 M |
08 Aug 2023 | $211.52 M |
07 Aug 2023 | $206.3 M |
04 Aug 2023 | $210.4 M |
03 Aug 2023 | $249.57 M |
02 Aug 2023 | $202.2 M |
01 Aug 2023 | $193.99 M |
31 Jul 2023 | $222.34 M |
28 Jul 2023 | $205.18 M |
27 Jul 2023 | $200.7 M |
26 Jul 2023 | $199.96 M |
25 Jul 2023 | $189.14 M |
24 Jul 2023 | $197.35 M |
21 Jul 2023 | $207.42 M |
20 Jul 2023 | $199.21 M |
19 Jul 2023 | $191.75 M |
18 Jul 2023 | $216.37 M |
17 Jul 2023 | $218.98 M |
14 Jul 2023 | $216.37 M |
13 Jul 2023 | $222.71 M |
12 Jul 2023 | $227 M |
11 Jul 2023 | $217.86 M |
10 Jul 2023 | $223.09 M |
07 Jul 2023 | $213.76 M |
06 Jul 2023 | $196.23 M |
05 Jul 2023 | $222.34 M |
03 Jul 2023 | $221.97 M |
30 Jun 2023 | $198.89 M |
29 Jun 2023 | $210.1 M |
28 Jun 2023 | $229.99 M |
27 Jun 2023 | $235.02 M |
26 Jun 2023 | $235.06 M |
23 Jun 2023 | $240.48 M |
22 Jun 2023 | $255.67 M |
21 Jun 2023 | $269.05 M |
20 Jun 2023 | $245 M |
16 Jun 2023 | $240.12 M |
15 Jun 2023 | $220.59 M |
14 Jun 2023 | $215.89 M |
13 Jun 2023 | $215.17 M |
12 Jun 2023 | $208.3 M |
09 Jun 2023 | $214.08 M |
08 Jun 2023 | $209.74 M |
07 Jun 2023 | $206.13 M |
06 Jun 2023 | $193.11 M |
05 Jun 2023 | $191.3 M |
02 Jun 2023 | $195.28 M |
01 Jun 2023 | $206.49 M |
31 May 2023 | $192.02 M |
30 May 2023 | $210.1 M |
26 May 2023 | $206.85 M |
25 May 2023 | $215.89 M |
24 May 2023 | $209.74 M |
23 May 2023 | $218.42 M |
22 May 2023 | $216.98 M |
19 May 2023 | $216.25 M |
18 May 2023 | $218.06 M |
17 May 2023 | $197.09 M |
16 May 2023 | $215.53 M |
15 May 2023 | $212.27 M |
12 May 2023 | $208.3 M |
11 May 2023 | $222.58 M |
10 May 2023 | $223.12 M |
09 May 2023 | $236.5 M |
08 May 2023 | $233.25 M |
05 May 2023 | $229.63 M |
04 May 2023 | $223.48 M |
03 May 2023 | $225.29 M |
02 May 2023 | $240.48 M |
01 May 2023 | $244.46 M |
28 Apr 2023 | $242.29 M |
27 Apr 2023 | $237.59 M |
26 Apr 2023 | $177.2 M |
25 Apr 2023 | $166.71 M |
24 Apr 2023 | $166.71 M |
21 Apr 2023 | $192.75 M |
20 Apr 2023 | $213.36 M |
19 Apr 2023 | $239.21 M |
18 Apr 2023 | $225.29 M |
17 Apr 2023 | $209.74 M |
14 Apr 2023 | $224.21 M |
13 Apr 2023 | $221.68 M |
12 Apr 2023 | $209.74 M |
11 Apr 2023 | $222.4 M |
10 Apr 2023 | $222.76 M |
06 Apr 2023 | $228.91 M |
05 Apr 2023 | $224.39 M |
04 Apr 2023 | $220.23 M |
03 Apr 2023 | $224.21 M |
31 Mar 2023 | $223.08 M |
30 Mar 2023 | $226.68 M |
29 Mar 2023 | $230.28 M |
28 Mar 2023 | $298.82 M |
27 Mar 2023 | $298.64 M |
24 Mar 2023 | $330.66 M |
23 Mar 2023 | $323.47 M |
22 Mar 2023 | $319.15 M |
21 Mar 2023 | $322.21 M |
20 Mar 2023 | $324.54 M |
17 Mar 2023 | $313.03 M |
16 Mar 2023 | $323.47 M |
15 Mar 2023 | $329.58 M |
14 Mar 2023 | $347.57 M |
13 Mar 2023 | $358.01 M |
10 Mar 2023 | $331.02 M |
09 Mar 2023 | $343.97 M |
08 Mar 2023 | $356.21 M |
07 Mar 2023 | $363.04 M |
06 Mar 2023 | $382.83 M |
03 Mar 2023 | $401.54 M |
02 Mar 2023 | $367.36 M |
01 Mar 2023 | $420.25 M |
28 Feb 2023 | $421.69 M |
27 Feb 2023 | $424.93 M |
24 Feb 2023 | $449.4 M |
23 Feb 2023 | $450.84 M |
22 Feb 2023 | $446.52 M |
21 Feb 2023 | $446.16 M |
17 Feb 2023 | $457.67 M |
16 Feb 2023 | $460.55 M |
15 Feb 2023 | $465.23 M |
14 Feb 2023 | $478.18 M |
13 Feb 2023 | $459.47 M |
10 Feb 2023 | $471.35 M |
09 Feb 2023 | $460.91 M |
08 Feb 2023 | $467.03 M |
07 Feb 2023 | $466.67 M |
06 Feb 2023 | $467.03 M |
03 Feb 2023 | $467.39 M |
02 Feb 2023 | $461.63 M |
01 Feb 2023 | $485.38 M |
31 Jan 2023 | $467.75 M |
30 Jan 2023 | $458.03 M |
27 Jan 2023 | $485.74 M |
26 Jan 2023 | $467.03 M |
25 Jan 2023 | $465.59 M |
24 Jan 2023 | $468.47 M |
23 Jan 2023 | $483.58 M |
20 Jan 2023 | $474.94 M |
19 Jan 2023 | $474.94 M |
18 Jan 2023 | $468.47 M |
17 Jan 2023 | $485.74 M |
13 Jan 2023 | $512.36 M |
12 Jan 2023 | $523.88 M |
11 Jan 2023 | $532.87 M |
10 Jan 2023 | $561.29 M |
09 Jan 2023 | $561.66 M |
06 Jan 2023 | $531.07 M |
05 Jan 2023 | $553.38 M |
04 Jan 2023 | $554.46 M |
03 Jan 2023 | $528.55 M |
30 Dec 2022 | $490.97 M |
29 Dec 2022 | $508.68 M |
28 Dec 2022 | $495.16 M |
27 Dec 2022 | $455.88 M |
23 Dec 2022 | $456.2 M |
22 Dec 2022 | $495.8 M |
21 Dec 2022 | $451.37 M |
20 Dec 2022 | $467.15 M |
19 Dec 2022 | $449.44 M |
16 Dec 2022 | $468.76 M |
15 Dec 2022 | $458.78 M |
14 Dec 2022 | $480.19 M |
13 Dec 2022 | $470.04 M |
12 Dec 2022 | $492.58 M |
09 Dec 2022 | $499.66 M |
08 Dec 2022 | $490.33 M |
07 Dec 2022 | $500.63 M |
06 Dec 2022 | $519.95 M |
05 Dec 2022 | $550.21 M |
02 Dec 2022 | $547.31 M |
01 Dec 2022 | $522.84 M |
30 Nov 2022 | $504.82 M |
29 Nov 2022 | $500.63 M |
28 Nov 2022 | $498.7 M |
25 Nov 2022 | $466.5 M |
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